Product Description

ZNF395 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-13288-60, E-AB-13288-120, E-AB-13288-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: ZNF395

Target Synonym: DKFZp434K1210; HD gene regulatory region binding protein 2; HD gene regulatory region-binding protein 2; HD-regulating factor 2; HDBP-2; HDBP2; HDRF-2; Huntington disease gene regulatory region-binding protein 2; Huntington's disease gene regulatory region binding protein 2; Papillomavirus regulatory factor 1; papillomavirus regulatory factor PRF 1; Papillomavirus-binding factor; PBF; PRF-1; PRF1; PTTG1IP; Si-1-8-14; Zinc finger protein 395; ZN395; znf395

Research Areas: Epigenetics and Nuclear Signaling, Microbiology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9H8N7

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF395 (Zinc finger protein 395), also known as PBF (Papillomavirus-binding factor) and HDBP2 (Huntington disease gene regulatory region-binding protein 2), is a 513 amino acid protein that contains one C2H2-type zinc finger. ZNF395 binds to the 3’-CCGG-5’ sequence within the papillomavirus promoter adjacent to a RUNX1-binding motif. It has also been established that ZNF395 binds to a seven base pair region within the Huntington's disease (HD) gene promoter, an essential element for HD gene expression. ZNF395 is widely expressed and probably shuttles between the nucleus and cytoplasm.

Concentration: 0.8 mg/mL

Immunogen: Synthetic peptide of human ZNF395

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only