Product Description

ZNF541 Polyclonal Antibody

Catalogue Numbers: BS2360-50, BS2360-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9H0D2

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF541 (zinc finger protein 541) is a 1,365 amino acid nuclear protein that acts as a component of a chromatin remodeling multiprotein complex involved in spermatogenesis. Existing as three alternatively spliced isoforms, ZNF541 interacts with both HSPA2 and HDAC1, and contains one SANT domain, a ELM2 domain and five C2H2-type zinc fingers. The gene encoding ZNF541 maps to human chromosome 19q13.33. Chromosome 19 consists of over 63 million bases, houses approximately 1,400 genes and is the genetic home for a number of immunoglobulin (Ig) superfamily members, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ZNF541 polyclonal antibody detects endogenous levels of ZNF541 protein.

Extra Notes: Western blot (WB) analysis of ZNF541 polyclonal antibody at 1:500 dilution
Lane1:H1792 whole cell lysate(40ug)
Lane2:A549 whole cell lysate(40ug)
Lane3:MCF-7 whole cell lysate(40ug)
Lane4:PMVEC whole cell lysate(40ug)
Lane5:3T3-L1 whole cell lysate(40ug)

Bioworld Molecular Weight: ~ 145 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Zinc finger protein 541; ZNF541

Immunogen: Synthetic peptide, corresponding Human ZNF541.

Conjugate: Unconjugated

Modification: Unmodified