Product Description

ZNF9 Polyclonal Antibody

Catalogue Numbers: BS60276-50, BS60276-100

Sizes: 50µl, 100µl

Alternative Name: Cellular nucleic acid-binding protein; CNBP; Zinc finger protein 9; CNBP; RNF163; ZNF9

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P62633

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Cellular nucleic acid binding protein (CNBP) is a highly conserved RNA-binding protein that plays a fundamental biological role in eukaryotic cells by increasing heterologous protein production. CNBP localizes to the nucleus of cells and functions in the brain, specifically in the anterior visceral endoderm and, subsequently, in the anterior definitive endoderm, anterior neuroectoderm, anterior mesendoderm, headfolds and forebrain. CNBP is necessary for the forebrain induction and specification, and mutations in the CNBP gene lead to severe forebrain truncation as well as various craniofacial defects due to a lack of proper morphogenetic movements of the anterior visceral endoderm during the pre-gastrulation stage. Overexpression of CNBP activates cell proliferation and stimulates the activity of the c-Myc promoter.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ZNF9 polyclonal antibody detects endogenous levels of ZNF9 protein.

Bioworld Molecular Weight: ~ 19 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of ZNF9 polyclonal antibody at 1:500 dilution
Lane 1: MCF-7 cell lysate
Lane 2: Raw264.7 cell lysate
Lane 3: Mouse brain tissue lysate

Immunogen: A synthetic peptide corresponding to residues in Human ZNF9.

Conjugate: Unconjugated

Modification: Unmodified