Product Description

ZNHIT1 Polyclonal Antibody

Catalogue Numbers: BS5982-50, BS5982-100

Sizes: 50µl, 100µl

Alternative Name: Zinc finger HIT domain-containing protein 1; Cyclin-G1-binding protein 1; Zinc finger protein subfamily 4A member 1; p18 Hamlet; CGBP1; ZNFN4A1

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O43257

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: ZNHIT1 (zinc finger, HIT-type containing 1), also known as CG1I (cyclin-G1-binding protein 1), p18 hamlet or ZNFN4A1 (zinc finger protein subfamily 4A member 1), is a 154 amino acid protein that plays a role in the induction of p53-mediated apoptosis. A member of the ZNHIT1 family, ZNHIT1 contains one HIT-type zinc finger and interacts with p38. ZNHIT1 undergoes post-translational phosphorylation and is encoded by a gene that maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ZNHIT1 polyclonal antibody detects endogenous levels of ZNHIT1 protein.

Bioworld Molecular Weight: ~ 18 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of ZNHIT1 polyclonal antibody at 1:500 dilution
Lane 1: Hela cell lysate
Lane 2: Mouse heart tissue lysate
Lane 3: Rat heart tissue lysate

Immunogen: Synthetic peptide, corresponding to amino acids 68-113 of Human ZNHIT1.

Conjugate: Unconjugated

Modification: Unmodified