ZnT-1 (R239) Polyclonal Antibody-BS9171

ZnT-1 (R239) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS9171-50, BS9171-100

Sizes: 50µl, 100µl

Swiss-Prot: Q9Y6M5

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

Background: Zinc, an essential element required for cell proliferation and differentiation, plays a role in a diverse array of cellular functions, including acting as a cofactor for numerous enzymes and transcription factors and as a neuroregulator. The zinc transporter (ZnT) family regulates the supply of zinc within cells, and its members are characterized by containing six membrane-spanning domains, a large histidine-rich intracellular loop, and a C-terminal tail. ZnT-1, a ubiquitous protein of approximately 60 kDa, localizes to the plasma membrane to aid in the export of zinc out of cells.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: ZnT-1 (R239) polyclonal antibody detects endogenous levels of ZnT-1 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of ZnT-1 (R239) pAb at 1:500 dilution
Lane 1: HCT116 whole cell lysate (40ug)
Lane 2: C6 whole cell lysate (40ug)
Lane 3: The Embryo tissue lysate of Mouse (40ug)
Lane 4: Hela whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of ZnT-1 (R239) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.

Bioworld Molecular Weight: ~ 55 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Zinc transporter 1; ZnT-1; Solute carrier family 30 member 1; SLC30A1; ZNT1

Immunogen: Synthetic peptide, corresponding to amino acids 200-250 of Human ZnT-1.

Conjugate: Unconjugated

Modification: Unmodified