ZO1 rabbit pAb - ES10356

ZO1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES10356-50, ES10356-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2014],

Source: Rabbit

Applications: WB; IF; ELISA

Dilution: WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from part region of human protein.AA1600-1700

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 192kD

Human Gene ID: 7082

Human SWISS Prot NO: Q07157

Subcellular Location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, tight junction. Cell junction. Cell junction, gap junction. Cell projection, podosome. Moves from the cytoplasm to the cell membrane concurrently with cell-cell contact (PubMed:7798316). At podosomal sites, is predominantly localized in the ring structure surrounding the actin core (PubMed:20930113). Colocalizes with SPEF1 at sites of cell-cell contact in intestinal epithelial cells (PubMed:31473225).

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