Product Description

ZWILCH Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-53208-60, E-AB-53208-120, E-AB-53208-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: ZWILCH  

Target Synonym: FLJ10036; FLJ16343; homolog of Drosophila Zwilch; hZwilch; KNTC1AP; MGC111034; Protein zwilch homolog; ZWILC; zwilch; zwilch kinetochore protein; ZWILCH protein; Zwilch; kinetochore associated; homolog

Research Areas: Cell Biology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9H900

Background: This protein is essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. And it is required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. ZWILCH gene is deleted in a patient suffering from colorectal cancer with chromosomal instability.

Concentration: 0.6 mg/mL

Immunogen: Synthetic peptide of human ZWILCH

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:1000-1:5000, ELISA 1:2000-1:10000

Calculated MW: 67 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only