Product Description

ZYX Polyclonal Antibody

Product: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16959-50, BZ16959-100

Swiss-Prot: Q15942

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC-P, ICC/IF, IP, FC

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100

Background: Zyxin binds alpha-actinin and the CRP proteins and is implicated in the regulation and modulation of actin filaments organization, cell adhesion, cell motility, mitosis, and signal transduction. Zyxin may shuttle between focal adhesion plaques and the nucleus. It has been suggested that zyxin is involved in gene transcription by its association with transcription factors in the nucleus.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Calculated MW: 61 kDa; Observed MW: 78 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Zyxin in MCF-7 lysates using ZYX antibody.

Alternative Name: ESP2; HED2; ZYX; Zyxin2

Immunogen: A synthesized peptide derived from human Zyxin

Conjugate: Unconjugated

Modification: Unmodified