Product Description

ZYX Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS46817-50, BS46817-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Focal adhesions are actin-rich structures that enable cells to adhere to the extracellμlar matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimμlated changes in gene expression and may modμlate the cytoskeletal organization of actin bundles. Alternative splicing resμlts in mμltiple transcript variants that encode the same isoform. [provided by RefSeq, Jμl 2008]

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IHC, ICC/IF, FC, IP

Alternate Names: ESP-2, HED-2

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide of human Zyxin

Dilution: WB: 1:2000-1:10000 IHC: 1:50 ICC/IF: 1:20-1:100 FC: 1:200-1:1000 IP: 1:20

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 78 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q15942

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only