ABCA1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A16337-20, A16337-100
Citations, Manuals and MSDS Available upon request.
Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency.
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, ELISA
Cross-reactivity: Mouse
Protein Weight: 254kDa
Observed Molecular Weight: 254kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 19
SWISS: O95477
Alternate Names: TGD; ABC1; CERP; ABC-1; HDLDT1; HPALP1; HDLCQTL13; ABCA1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Lipid Metabolism, Cholesterol Metabolism, Neuroscience, Cell Type Marker, Cardiovascular, Heart, Lipids, Cardiovascular diseases, Heart disease, Astrocyte marker.
NCBI Alias: ABCA1
Research Use Only