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AIMP1 Rabbit pAb - A5301

AIMP1 Rabbit pAb - A5301

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AIMP1 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A5301-20, A5301-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20.

Category: Polyclonal Antibodies

Applications: WB, IHC-P, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 34kDa

Observed Molecular Weight: 37kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 9255

SWISS: Q12904

Alternate Names: p43; HLD3; EMAP2; SCYE1; EMAPII; AIMP1

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, Cancer, Tumor biomarkers, Kinase, Cell Biology Developmental Biology, Apoptosis, Immunology Inflammation, Cytokines, Cell Intrinsic Innate Immunity Signaling Pathway, Cardiovascular, Angiogenesis.

NCBI Alias: AIMP1

Research Use Only