AKR7A2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A1227-20, A1227-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 40kDa
Observed Molecular Weight: 35kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 8574
SWISS: O43488
Alternate Names: AFAR; AKR7; AFAR1; AFB1-AR1; AKR7A2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Endocrine Metabolism, Neuroscience, Neurodegenerative Diseases.
NCBI Alias: AKR7A2
Research Use Only