Alpha-1 Antichymotrypsin (SERPINA3) Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A1021-20, A1021-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. This gene is one in a cluster of serpin genes located on the q arm of chromosome 14. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Human
Protein Weight: 48kDa
Observed Molecular Weight: 50-76kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 12
SWISS: P01011
Alternate Names: ACT; AACT; GIG24; GIG25; Alpha-1 Antichymotrypsin (SERPINA3)
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:100 - 1:500 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cell Biology Developmental Biology, Ubiquitin, Neuroscience, Neurodegenerative Diseases, Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease, Cardiovascular, Blood, Serum Proteins.
NCBI Alias: SERPINA3
Research Use Only