Alpha-1 Antitrypsin (SERPINA1) Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A12481-20, A12481-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a serine protease inhibitor belonging to the serpin superfamily whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. This protein is produced in the liver, the bone marrow, by lymphocytic and monocytic cells in lymphoid tissue, and by the Paneth cells of the gut. Defects in this gene are associated with chronic obstructive pulmonary disease, emphysema, and chronic liver disease. Several transcript variants encoding the same protein have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 47kDa
Observed Molecular Weight: 45kDa, 50kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 5265
SWISS: P01009
Alternate Names: PI; A1A; AAT; PI1; A1AT; nNIF; PRO2275; alpha1AT; Alpha-1 Antitrypsin (SERPINA1)
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Endocrine Metabolism, Cardiovascular, Blood, Serum Proteins, Hypoxia.
NCBI Alias: SERPINA1
Research Use Only