alpha 1 Spectrin Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A12355-20, A12355-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of a family of molecular scaffold proteins that link the plasma membrane to the actin cytoskeleton and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms a component of the erythrocyte plasma membrane. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis-2, pyropoikilocytosis, and spherocytosis, type 3.
Category: Polyclonal Antibodies
Applications: WB, IF-P, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 280kDa
Observed Molecular Weight: 300kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 6708
SWISS: P02549
Alternate Names: EL2; HPP; HS3; SPH3; SPTA; alpha 1 Spectrin
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IF-P, 1:50 - 1:200 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Cytoskeleton, Microfilaments, Cardiovascular, Blood.
NCBI Alias: SPTA1
Research Use Only