ALPK1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A24028-20, A24028-100
Citations, Manuals and MSDS Available upon request.
Background: Alpha-protein kinase 1, also known as alpha-kinase 1 (ALPK1), is associated with chronic kidney disease (CKD), myocardial infarction, gout and type 2 diabetes mellitus (DM) . ALPK1 mutant has been reported to cause severe defects in motor co‐ordination in mice. ALPK1 enhances the expression of proinflammatory cytokines including IL-1β, IL-8 and TGF-β1 in cultured human THP1 and human embryonic kidney 293 (HEK293) cells . ALPK1 short isoform (108 kDa) was highly expressed in brain, spinal cord, heart, lung, spleen, thymus, small intestine, skin and testis, while detectable inskeletal muscle and kidney. ALPK1 large isoform (130 kDa) appeared in heart, lung, thymus and skin.
Category: Polyclonal Antibodies
Applications: WB
Cross-reactivity: Human
Protein Weight: 139kDa
Observed Molecular Weight: 150kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 80216
SWISS: Q96QP1
Alternate Names: LAK; ROSAH; 8430410J10Rik; ALPK1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000
Research Areas: Signal Transduction;Protein Trafficking;Vesicle Transport;Regulation.
NCBI Alias: ALPK1
Research Use Only