APOA1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A14211-20, A14211-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Mouse, Rat
Protein Weight: 28kDa
Observed Molecular Weight: 31kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 335
SWISS: P02647
Alternate Names: HPALP2; apo (a) ; APOA1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Lipid Metabolism, Neuroscience, Neurodegenerative Diseases, Cardiovascular, Heart, Lipids, Cardiovascular diseases, Heart disease.
NCBI Alias: APOA1
Research Use Only