APPL1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A4606-20, A4606-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 80kDa
Observed Molecular Weight: 95kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 26060
SWISS: Q9UKG1
Alternate Names: APPL; MODY14; DIP13alpha; APPL1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Neuroscience.
NCBI Alias: APPL1
Research Use Only