ARHGDIB Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A3740-20, A3740-100
Citations, Manuals and MSDS Available upon request.
Background: Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs) . The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]) .
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 23kDa
Observed Molecular Weight: 23kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 397
SWISS: P52566
Alternate Names: D4; GDIA2; GDID4; LYGDI; Ly-GDI; RAP1GN1; RhoGDI2; ARHGDIB
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, G protein signaling, Small G proteins, Cell Biology Developmental Biology, Cytoskeleton, Microfilaments.
NCBI Alias: ARHGDIB
Research Use Only