AscL1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A10669-20, A10669-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Mouse, Rat
Protein Weight: 25kDa
Observed Molecular Weight: 30kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 429
SWISS: P50553
Alternate Names: ASH1; HASH1; MASH1; bHLHa46; AscL1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:100 - 1:500 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Neuroscience.
NCBI Alias: ASCL1
Research Use Only