BAG2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A7763-20, A7763-100
Citations, Manuals and MSDS Available upon request.
Background: BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human
Protein Weight: 24kDa
Observed Molecular Weight: 24kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 9532
SWISS: O95816
Alternate Names: BAG-2; dJ417I1.2; BAG2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Invasion and Metastasis, Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Endocrine Metabolism.
NCBI Alias: BAG2
Research Use Only