Bcl-2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A11025-20, A11025-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 26kDa
Observed Molecular Weight: 26kDa/
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 596
SWISS: P10415
Alternate Names: Bcl-2; PPP1R50
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:100 - 1:500 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Protein phosphorylation, Cancer, Tumor biomarkers, Invasion and Metastasis, Signal Transduction, PI3K-Akt Signaling Pathway, Cell Biology Developmental Biology, Apoptosis, Mitochondrial Control of Apoptosis, Inhibition of Apoptosis, Autophagy, Death Receptor Signaling Pathway, Endocrine Metabolism, Mitochondrial metabolism, Mitochondrial markers, Immunology Inflammation, Neuroscience, Neurodegenerative Diseases, Stem Cells.
NCBI Alias: BCL2
Research Use Only