Bcl-2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A25052-20, A25052-100
Citations, Manuals and MSDS Available upon request.
Background: Enables BH domain binding activity. Involved in several processes, including response to peptide; response to purine-containing compound; and response to vitamin. Located in cytosol; mitochondrial crista; and perinuclear region of cytoplasm. Used to study several diseases, including brain ischemia (multiple) ; end stage renal disease; gastric ulcer; intestinal disease (multiple) ; and status epilepticus. Biomarker of several diseases, including abdominal obesity-metabolic syndrome 1; brain disease (multiple) ; hypertension (multiple) ; intrinsic cardiomyopathy (multiple) ; and neurodegenerative disease (multiple) . Human ortholog (s) of this gene implicated in several diseases, including carcinoma (multiple) ; hematologic cancer (multiple) ; intracranial aneurysm; prostate cancer; and urinary bladder cancer. Orthologous to human BCL2 (BCL2 apoptosis regulator) .
Category: Polyclonal Antibodies
Applications: WB, IP, ELISA
Cross-reactivity: Mouse
Protein Weight: 26kDa
Observed Molecular Weight: 26kDa
Immunogen: Recombinant protein (or fragment) .
Species: Rat
GeneID: 24224
SWISS: P49950
Alternate Names: Bcl-2,
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:1000 - 1:5000 IP, 0.5μg-4μg antibody for 400μg-600μg extracts of whole cells ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Apoptosis regulation, Autophagy signal transduction, Ddeath receptor signal transduction.
NCBI Alias: Bcl-2
Research Use Only