BMP3 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A6877-20, A6877-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 53kDa
Observed Molecular Weight: 53kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 651
SWISS: P12645
Alternate Names: BMP-3A; BMP3
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:100 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Cytoskeleton, Extracellular Matrix, Bone, Growth factors, Wnt -Catenin Signaling Pathway, Immunology Inflammation, Cytokines, NF-kB Signaling Pathway.
NCBI Alias: BMP3
Research Use Only