BMP6 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A15648-20, A15648-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients.
Category: Polyclonal Antibodies
Applications: IF/ICC, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 57kDa
Observed Molecular Weight: Refer to figures
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 654
SWISS: P22004
Alternate Names: IO; VGR; VGR1; BMP6
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: IF/ICC, 1:100 - 1:500 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Cell Cycle, Cell differentiation, Cytoskeleton, Extracellular Matrix, Bone, Growth factors, Wnt -Catenin Signaling Pathway, ESC Pluripotency and Differentiation, Immunology Inflammation, NF-kB Signaling Pathway, Stem Cells.
NCBI Alias: BMP6
Research Use Only