BRE Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A15122-20, A15122-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer.
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, IF-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 44kDa
Observed Molecular Weight: 44kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 9577
SWISS: Q9NXR7
Alternate Names: BRE; BRCC4; BRCC45
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:200 IF-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, DNA Damage Repair, Cancer, Tumor suppressors, p53 pathway, Cell Biology Developmental Biology, Apoptosis, Cell Cycle, Cell cycle inhibitors, Ubiquitin, Immunology Inflammation, Cytokines.
NCBI Alias: BABAM2
Research Use Only