CAPN3 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A11995-20, A11995-100
Citations, Manuals and MSDS Available upon request.
Background: Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, ELISA
Cross-reactivity: Mouse, Rat
Protein Weight: 94kDa
Observed Molecular Weight: 114kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 825
SWISS: P20807
Alternate Names: p94; CANP3; LGMD2; nCL-1; CANPL3; LGMD2A; LGMDD4; LGMDR1; CAPN3
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Ubiquitin, Neuroscience, Calcium Signaling.
NCBI Alias: CAPN3
Research Use Only