CARD8 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A0293-20, A0293-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene belongs to the caspase recruitment domain (CARD) -containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human
Protein Weight: 61kDa
Observed Molecular Weight: 60kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 22900
SWISS: Q9Y2G2
Alternate Names: NDPP; DACAR; DAKAR; NDPP1; TUCAN; CARDINAL; CARD8
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cell Biology Developmental Biology, Apoptosis, Caspases.
NCBI Alias: CARD8
Research Use Only