Caspase-1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A20470-20, A20470-100
Citations, Manuals and MSDS Available upon request.
Background: Enables cysteine-type endopeptidase activity. Involved in several processes, including positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of interleukin-1 beta production; and protein autoprocessing. Acts upstream of or within several processes, including membrane hyperpolarization; mitochondrial depolarization; and positive regulation of interleukin-1 alpha production. Located in extracellular region. Part of IPAF inflammasome complex. Is expressed in knee joint and metanephros. Orthologous to human CASP1 (caspase 1).
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Mouse
Protein Weight: 46kDa
Observed Molecular Weight: 48kDa
Immunogen: Synthetic peptide
Species: Mouse
GeneID: 12362
SWISS: P29452
Alternate Names: ICE; Il1bc; CASP1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
NCBI Alias: Casp1
Research Use Only