Caspase-2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A5724-20, A5724-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 51kDa
Observed Molecular Weight: 48kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 835
SWISS: P42575
Alternate Names: ICH1; NEDD2; CASP-2; NEDD-2; PPP1R57; Caspase-2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Invasion and Metastasis, Signal Transduction, ErbB-HER Signaling Pathway, Cell Biology Developmental Biology, Apoptosis, Caspases, Mitochondrial Control of Apoptosis, Ubiquitin, Endocrine Metabolism, Immunology Inflammation.
NCBI Alias: CASP2
Research Use Only