CCDC88A Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A16132-20, A16132-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K) -dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human
Protein Weight: 216kDa
Observed Molecular Weight: 220kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 55704
SWISS: Q3V6T2
Alternate Names: APE; GIV; GRDN; PEHO; HkRP1; PEHOL; GIRDIN; KIAA1212; CCDC88A
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Cell Adhesion, Cytoskeleton, Microtubules, Neuroscience.
NCBI Alias: CCDC88A
Research Use Only