CD177 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A6550-20, A6550-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a glycosyl-phosphatidylinositol (GPI) -linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 51kDa
Observed Molecular Weight: 105kDa/45kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 57126
SWISS: Q8N6Q3
Alternate Names: NB1; PRV1; HNA2A; PRV-1; HNA-2a; NB1 GP; CD177
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Immunology Inflammation, CDs.
NCBI Alias: CD177
Research Use Only