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CD31/PECAM1 Rabbit pAb - A3181

CD31/PECAM1 Rabbit pAb - A3181

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CD31/PECAM1 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A3181-20, A3181-100

Citations, Manuals and MSDS Available upon request.

Background: Predicted to enable protein homodimerization activity; protein phosphatase binding activity; and transmembrane signaling receptor activity. Acts upstream of or within several processes, including Rho protein signal transduction; endothelial cell morphogenesis; and positive regulation of tyrosine phosphorylation of STAT protein. Located in several cellular components, including cell-cell contact zone; external side of plasma membrane; and smooth muscle contractile fiber. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; extraembryonic component; and genitourinary system. Human ortholog (s) of this gene implicated in coronary artery disease (multiple) ; lung non-small cell carcinoma; neuroblastoma; and psoriatic arthritis. Orthologous to human PECAM1 (platelet and endothelial cell adhesion molecule 1) .

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Human, Mouse

Protein Weight: 81kDa

Observed Molecular Weight: 130kDa

Immunogen: Recombinant protein (or fragment) .

Species: Mouse

GeneID: 18613

SWISS: Q08481

Alternate Names: Cd31; Pecam; PECAM-1; CD31/PECAM1

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:100 - 1:500 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Cancer, Tumor immunology, Invasion and Metastasis, Signal Transduction, Cell Biology & Developmental Biology, Cell Adhesion, Cell Adhesion Molecules, Cytoskeleton, Immunology & Inflammation, CD markers, Stem Cells, Hematopoietic Progenitors, Mesenchymal Stem Cells, Cardiovascular, Angiogenesis, Blood.

NCBI Alias: Pecam1

Research Use Only