CD4 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A0362-20, A0362-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, IF-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 51kDa
Observed Molecular Weight: 51kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 920
SWISS: P01730
Alternate Names: T4; IMD79; Leu-3; OKT4D; CD4mut; CD4
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:200 IF-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Immunology Inflammation, CDs, T Cell Receptor Signaling Pathway, Stem Cells, Hematopoietic Progenitors.
NCBI Alias: CD4
Research Use Only