CENPA Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A15995-20, A15995-100
Citations, Manuals and MSDS Available upon request.
Background: Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4) 2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human
Protein Weight: 16kDa
Observed Molecular Weight: 18kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 1058
SWISS: P49450
Alternate Names: CenH3; CENP-A; CENPA
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Protein phosphorylation, Cell Biology Developmental Biology, Cell Cycle.
NCBI Alias: CENPA
Research Use Only