CENPE Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A15263-20, A15263-100
Citations, Manuals and MSDS Available upon request.
Background: Centrosome-associated protein E (CENPE) is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. This protein is required for stable spindle microtubule capture at kinetochores which is a necessary step in chromosome alignment during prometaphase. This protein also couples chromosome position to microtubule depolymerizing activity. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 316kDa
Observed Molecular Weight: 270kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 1062
SWISS: Q02224
Alternate Names: KIF10; CENP-E; MCPH13; PPP1R61; CENPE
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:200 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Cell Biology Developmental Biology, Cell Cycle.
NCBI Alias: CENPE
Research Use Only