CHD4 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A11574-20, A11574-100
Citations, Manuals and MSDS Available upon request.
Background: The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 218kDa
Observed Molecular Weight: 280kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 1108
SWISS: Q14839
Alternate Names: CHD-4; Mi-2b; SIHIWES; Mi2-BETA; CHD4
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:100 - 1:200 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Chromatin Remodeling, Immunology Inflammation.
NCBI Alias: CHD4
Research Use Only