CHMP2B Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A13410-20, A13410-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 24kDa
Observed Molecular Weight: 28kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 25978
SWISS: Q9UQN3
Alternate Names: DMT1; ALS17; VPS2B; VPS2-2; CHMP2.5; FTDALS7; CHMP2B
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Autophagy, Neuroscience, Neurodegenerative Diseases.
NCBI Alias: CHMP2B
Research Use Only