COL9A1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A6563-20, A6563-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Rat
Protein Weight: 92kDa
Observed Molecular Weight: 92kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 1297
SWISS: P20849
Alternate Names: MED; EDM6; STL4; DJ149L1.1.2; COL9A1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Cytoskeleton, Extracellular Matrix.
NCBI Alias: COL9A1
Research Use Only