Complement factor D Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A22110-20, A22110-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human
Protein Weight: 27kDa
Observed Molecular Weight: 27kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 1675
SWISS: P00746
Alternate Names: DF; ADN; PFD; ADIPSIN; Complement factor D
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:100 - 1:500 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Immunology Inflammation, Cell Intrinsic Innate Immunity Signaling Pathway.
NCBI Alias: CFD
Research Use Only