CRM1/XPO1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A0299-20, A0299-100
Citations, Manuals and MSDS Available upon request.
Background: This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES) -dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 123kDa
Observed Molecular Weight: 123kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 7514
SWISS: O14980
Alternate Names: emb; CRM1; exp1; CRM-1; CRM1/XPO1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Nuclear Receptor Signaling, Signal Transduction, Cell Biology Developmental Biology, Cell Cycle, Centrosome.
NCBI Alias: XPO1
Research Use Only