CTSK Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A1782-20, A1782-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 37kDa
Observed Molecular Weight: 26kDa/37kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 1513
SWISS: P43235
Alternate Names: CTSO; PKND; PYCD; CTS02; CTSO1; CTSO2; CTSK
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:100 - 1:500 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Invasion and Metastasis, Signal Transduction, Cell Biology Developmental Biology, Cell Adhesion, Cytoskeleton, Extracellular Matrix, Ubiquitin, Neuroscience, Cardiovascular, Angiogenesis.
NCBI Alias: CTSK
Research Use Only