CUL4B Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A12696-20, A12696-100
Citations, Manuals and MSDS Available upon request.
Background: This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 104kDa
Observed Molecular Weight: 105kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 8450
SWISS: Q13620
Alternate Names: SFM2; MRXSC; CUL-4B; MRXHF2; MRXS15; CUL4B
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cell Biology Developmental Biology, Ubiquitin, Ubiquitin-Proteasome Signaling Pathway.
NCBI Alias: CUL4B
Research Use Only