CYLD Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A3821-20, A3821-100
Citations, Manuals and MSDS Available upon request.
Background: This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 107kDa
Observed Molecular Weight: 107kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 1540
SWISS: Q9NQC7
Alternate Names: EAC; MFT; SBS; TEM; BRSS; CDMT; MFT1; CYLD1; CYLDI; USPL2; FTDALS8; CYLD
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:100 - 1:500 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Cancer, Tumor suppressors, Cell Biology Developmental Biology, Apoptosis, Inhibition of Apoptosis, Ubiquitin, Death Receptor Signaling Pathway, Wnt -Catenin Signaling Pathway, Immunology Inflammation, NF-kB Signaling Pathway.
NCBI Alias: CYLD
Research Use Only