CYP11B1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A15046-20, A15046-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene.
Category: Polyclonal Antibodies
Applications: IHC-P, IF/ICC, ELISA
Cross-reactivity: Human
Protein Weight: 58kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 1584
SWISS: P15538
Alternate Names: FHI; CPN1; CYP11B; P450C11; CYP11B1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: IHC-P, 1:2000 - 1:8000 IF/ICC, 1:2000 - 1:8000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, Cell Biology Developmental Biology, Growth factors, Endocrine Metabolism, Mitochondrial metabolism, Mitochondrial markers, Lipid Metabolism, Lipases, Cardiovascular, Lipids.
NCBI Alias: CYP11B1
Research Use Only