DGCR8 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A18630-20, A18630-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IP, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 86kDa
Observed Molecular Weight: 110kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 54487
SWISS: Q8WYQ5
Alternate Names: Gy1; pasha; DGCRK6; C22orf12; DGCR8
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:200 IP, 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Nuclear Receptor Signaling.
NCBI Alias: DGCR8
Research Use Only