DLK1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A2715-20, A2715-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 41kDa
Observed Molecular Weight: 41kDa/
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 8788
SWISS: P80370
Alternate Names: DLK; FA1; ZOG; pG2; DLK-1; PREF1; Delta1; Pref-1; DLK1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:100 IF/ICC, 1:50 - 1:100 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Epigenetic writers and erasers of core Histones, Signal Transduction, Endocrine Metabolism, Neuroscience, Calcium Signaling, Stem Cells, Hematopoietic Progenitors.
NCBI Alias: DLK1
Research Use Only