DNAJC2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A4633-20, A4633-100
Citations, Manuals and MSDS Available upon request.
Background: This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 72kDa
Observed Molecular Weight: 80kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 27000
SWISS: Q99543
Alternate Names: ZRF1; ZUO1; MPP11; MPHOSPH11; DNAJC2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, RNA Binding, Cancer, Tumor immunology, Tumor-associated antigens, Signal Transduction, Immunology Inflammation.
NCBI Alias: DNAJC2
Research Use Only