DPYD Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A1620-20, A1620-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 111kDa
Observed Molecular Weight: 112kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 1806
SWISS: Q12882
Alternate Names: DHP; DPD; DYPD; DHPDHASE; DPYD
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Endocrine Metabolism, Amino acid metabolism.
NCBI Alias: DPYD
Research Use Only