DSC2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A10211-20, A10211-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human
Protein Weight: 100kDa
Observed Molecular Weight: 100kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 1824
SWISS: Q02487
Alternate Names: DG2; DSC3; CDHF2; ARVD11; DGII/III; DSC2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:1000 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Cell Adhesion, Cadherins, Cytoskeleton, Extracellular Matrix, Cardiovascular, Heart, Cardiac arrhythmias.
NCBI Alias: DSC2
Research Use Only